Dental malformations associated with biallelic MMP20 mutations

Dental malformations associated with biallelic MMP20 mutations

Abstract Background Matrix metallopeptidase 20 (MMP20) is an evolutionarily conserved protease that is essential for processing enamel matrix proteins during dental enamel formation. MMP20 mutations cause human autosomal recessive pigmented hypomaturation‐type amelogenesis imperfecta (AI2A2; OMIM #6...

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Bibliographic Details
Main Authors: Shih‐Kai Wang, Hong Zhang, Michael B. Chavez, Yuanyuan Hu, Figen Seymen, Mine Koruyucu, Yelda Kasimoglu, Connor D. Colvin, Tamara N. Kolli, Michelle H. Tan, Yin‐Lin Wang, Pei‐Ying Lu, Jung‐Wook Kim, Brian L. Foster, John D. Bartlett, James P. Simmer, Jan C.‐C. Hu
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
amelogenesis imperfecta
enamel hardness
dentin defects
hypomineralization
MMP20 mutations
Online Access:https://doi.org/10.1002/mgg3.1307

Internet

https://doi.org/10.1002/mgg3.1307

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