Transcription of the human and rodent <it>SPAM1 / PH-20 </it>genes initiates within an ancient endogenous retrovirus

<p>Abstract</p> <p>Background</p> <p>Sperm adhesion molecule 1 (SPAM1) is the major mammalian testicular hyaluronidase and is expressed at high levels in sperm cells. SPAM1 protein is important for penetration of the cumulus cell layer surrounding the ovum, and is also...

Full description

Bibliographic Details
Main Authors: Dunn Catherine A, Mager Dixie L
Format: Article
Language:English
Published: BMC 2005-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/6/47