The role of SIRT1 in the pathogenesis of insulin resistance in skeletal muscle

The role of SIRT1 in the pathogenesis of insulin resistance in skeletal muscle

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Skeletal muscle insulin resistance manifests as a decreased ability of insulin to stimulate glucose uptake in consequence of an impairment in its intracellular signaling. Sirtuin 1 (SIRT1), which belongs to the family of sirtuins (Sir2; silent information regulator 2 protein) participates in the reg...

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Bibliographic Details
Main Authors: Magdalena Stefanowicz, Marek Strączkowski, Monika Karczewska-Kupczewska
Format: Article
Language:English
Published: Index Copernicus International S.A. 2015-01-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
SIRT1
AMPK
Insulin Resistance
skeletal muscle
Online Access:http://phmd.publisherspanel.com/portal/icid/1136379

Internet

http://phmd.publisherspanel.com/portal/icid/1136379

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