Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase

Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase

Hypertension is a major cause of heart attack and stroke. Our recent study revealed that gallic acid (GA) exerts protective effects on pressure overload-induced cardiac hypertrophy and dysfunction. However, the role of GA in angiotensin II (Ang II)-induced hypertension and vascular remodeling remain...

Full description

Bibliographic Details
Main Authors: Xiao Yan, Qi-Yu Zhang, Yun-Long Zhang, Xiao Han, Shu-Bin Guo, Hui-Hua Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
gallic acid
angiotensin II
hypertension
immunoproteasome
eNOS degradation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01121/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01121/full

Similar Items