Selective vulnerability of cerebral white matter in a murine model of multiple sclerosis detected using diffusion tensor imaging

In this study, axial (λ||) and radial (λ⊥) diffusivities derived from diffusion tensor imaging (DTI) were used to evaluate white matter injury in brains of mice affected by experimental autoimmune encephalomyelitis (EAE). Sixteen female C57BL/6 mice were immunized with amino acids 35–55 of myelin ol...

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Bibliographic Details
Main Authors: Shu-Wei Sun, Hsiao-Fang Liang, Robert E. Schmidt, Anne H. Cross, Sheng-Kwei Song
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Neurobiology of Disease
Subjects:
EAE
MOG
DTI
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107001313