Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model

The canonical nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway regulates central processes in mammalian cells and plays a fundamental role in the regulation of inflammation and immunity. Aberrant regulation of the activation of the transcription facto...

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Bibliographic Details
Main Authors: Uwe Benary, Jana Wolf
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/7/2/40