The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure

The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure

Background: Studies reporting accelerated ageing in children with affective disorders or maltreatment exposure have relied on algorithms for estimating epigenetic age derived from adult samples. These algorithms have limited validity for epigenetic age estimation during early development. We here us...

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Bibliographic Details
Main Authors: Felix Dammering, Jade Martins, Katja Dittrich, Darina Czamara, Monika Rex-Haffner, Judith Overfeld, Karin de Punder, Claudia Buss, Sonja Entringer, Sibylle M. Winter, Elisabeth B. Binder, Christine Heim
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Stress
Subjects:
Epigenetic ageing
Early development
Maltreatment
Psychopathology
Glucocorticoids
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289521001028

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http://www.sciencedirect.com/science/article/pii/S2352289521001028

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