Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

Quantitative phosphoproteomics of proteasome inhibition in multiple myeloma cells.

<h4>Background</h4>The proteasome inhibitor bortezomib represents an important advance in the treatment of multiple myeloma (MM). Bortezomib inhibits the activity of the 26S proteasome and induces cell death in a variety of tumor cells; however, the mechanism of cytotoxicity is not well...

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Main Authors: Feng Ge, Chuan-Le Xiao, Li-Jun Bi, Sheng-Ce Tao, Sheng Xiong, Xin-Feng Yin, Li-Ping Li, Chun-Hua Lu, Hai-Tao Jia, Qing-Yu He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20927383/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20927383/?tool=EBI

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