High-Performance Mixed Models Based Genome-Wide Association Analysis with omicABEL software [v1; ref status: indexed, http://f1000r.es/40b]

To raise the power of genome-wide association studies (GWAS) and avoid false-positive results in structured populations, one can rely on mixed model based tests. When large samples are used, and when multiple traits are to be studied in the ’omics’ context, this approach becomes computationally chal...

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Bibliographic Details
Main Authors: Diego Fabregat-Traver, Sodbo Zh. Sharapov, Caroline Hayward, Igor Rudan, Harry Campbell, Yurii Aulchenko, Paolo Bientinesi
Format: Article
Language:English
Published: F1000 Research Ltd 2014-08-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-200/v1