The Mode-of-Action of Targeted Alpha Therapy Radium-223 as an Enabler for Novel Combinations to Treat Patients with Bone Metastasis

Bone metastasis is a common clinical complication in several cancer types, and it causes a severe reduction in quality of life as well as lowering survival time. Bone metastases proceed through a vicious self-reinforcing cycle that can be osteolytic or osteoblastic in nature. The vicious cycle is ch...

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Bibliographic Details
Main Authors: Mari I. Suominen, Timothy Wilson, Sanna-Maria Käkönen, Arne Scholz
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
TAT
Online Access:https://www.mdpi.com/1422-0067/20/16/3899