Characterization of clinically-attenuated Burkholderia mallei by whole genome sequencing: candidate strain for exclusion from Select Agent lists.

Characterization of clinically-attenuated Burkholderia mallei by whole genome sequencing: candidate strain for exclusion from Select Agent lists.

Burkholderia mallei is an understudied biothreat agent responsible for glanders which can be lethal in humans and animals. Research with this pathogen has been hampered in part by constraints of Select Agent regulations for safety reasons. Whole genomic sequencing (WGS) is an apt approach to charact...

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Bibliographic Details
Main Authors: Steven E Schutzer, Linda R K Schlater, Catherine M Ronning, David DeShazer, Benjamin J Luft, John J Dunn, Jacques Ravel, Claire M Fraser-Liggett, William C Nierman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2312325?pdf=render

Internet

http://europepmc.org/articles/PMC2312325?pdf=render

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