Mutational spectrum of <it>APC </it>and genotype-phenotype correlations in Greek FAP patients

<p>Abstract</p> <p>Background</p> <p>Familial adenomatous polyposis, an autosomal dominant inherited disease caused by germline mutations within the <it>APC </it>gene, is characterized by early onset colorectal cancer as a consequence of the intrinsic phenot...

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Bibliographic Details
Main Authors: Fountzilas George, Sandaltzopoulos Raphael, Thodi Georgia, Fostira Florentia, Yannoukakos Drakoulis
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/389