Pretreatment of Ascorbic Acid Inhibits MPTP-Induced Astrocytic Oxidative Stress through Suppressing NF-κB Signaling

Astrocytes are a major constituent of the central nervous system (CNS). Astrocytic oxidative stress contributes to the development of Parkinson’s disease (PD). Maintaining production of antioxidant and detoxification of reactive oxygen and nitrogen species (ROS/RNS) in astrocytes is critical to prev...

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Bibliographic Details
Main Authors: Xiaokang Zeng, Kai Xu, Ji Wang, Yunqi Xu, Shaogang Qu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2020/8872296