Lithium Chloride Suppresses Colorectal Cancer Cell Survival and Proliferation through ROS/GSK-3β/NF-κB Signaling Pathway

Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, has been regarded as a potential therapeutic target for multiple human cancers. In addition, oxidative stress is closely related to all aspects of cancer. We sought to determine the biological function of lithium, one kind of G...

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Bibliographic Details
Main Authors: Huili Li, Kun Huang, Xinghua Liu, Jinlin Liu, Xiaoming Lu, Kaixiong Tao, Guobin Wang, Jiliang Wang
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2014/241864