Toll-like receptor 2/6-dependent stimulation of mesenchymal stem cells promotes angiogenesis by paracrine factors

Toll-like receptor 2/6-dependent stimulation of mesenchymal stem cells promotes angiogenesis by paracrine factors

Reconstruction of critical size bone defects represents a major challenge in orthopaedic surgery. Insufficient angiogenesis is a limiting factor for engraftment of large-scale tissue transplants. Transplantation or stimulation of local mesenchymal stem cells (MSCs) represents a potential solution to...

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Bibliographic Details
Main Authors: H Kokemüller, M Luchtefeld, S Spalthoff, P Jehn, C Liu, M Petri, K Grote, T Tschernig, C Krettek, C Haasper, M Jagodzinski
Format: Article
Language:English
Published: AO Research Institute Davos 2013-09-01
Series:European Cells & Materials
Subjects:
Tissue engineering
angiogenesis
Toll-like receptors
mesenchymal stem cells
growth factors
Online Access:http://www.ecmjournal.org/journal/papers/vol026/pdf/v026a05.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol026/pdf/v026a05.pdf

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