PNPLA2 influences secretion of triglyceride-rich lipoproteins by human hepatoma cells

PNPLA2 influences secretion of triglyceride-rich lipoproteins by human hepatoma cells

Patatin-like phospholipase domain-containing proteins (PNPLAs) are involved in triglyceride hydrolysis and lipid-droplet homeostasis in mice, but the physiological significance of the PNPLAs for triglyceride metabolism in human hepatocytes is unclear. Here, we investigate the roles of PNPLA2, PNPLA3...

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Bibliographic Details
Main Authors: Apostolos Taxiarchis, Hovsep Mahdessian, Angela Silveira, Rachel M. Fisher, Ferdinand M. van't Hooft
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Journal of Lipid Research
Subjects:
endoplasmic reticulum
lipid droplets
lipolysis and fatty acid metabolism
liver
nonalcoholic fatty liver disease
triglycerides/diacylglycerol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322471

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http://www.sciencedirect.com/science/article/pii/S0022227520322471

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