A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome

A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome

Abstract Background Hereditary cancer syndromes have inherited germline mutations which predispose to benign and malignant tumors. Understanding of the molecular causes in hereditary cancer syndromes has advanced cancer treatment and prevention. However, the causal genes of many hereditary cancer sy...

Full description

Bibliographic Details
Main Authors: Yanting Jiang, Yue Sun, Jiandong Hu, Nan Yu, Hui Liu, Jiankun Fan, Xuelian Ning, Yilan Li, Baogang Liu, Yihua Sun, Jinwei Zhang, Xiaohong Qiu, Songbin Fu, Chunshui Zhou, Hui Xu
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Cancer
Subjects:
Hereditary cancer syndrome
Germline mutation
Whole-exome sequencing
Rab43
Online Access:http://link.springer.com/article/10.1186/s12885-019-5845-4

Internet

http://link.springer.com/article/10.1186/s12885-019-5845-4

Similar Items