Antimycobacterial and Anti-Inflammatory Activities of Substituted Chalcones Focusing on an Anti-Tuberculosis Dual Treatment Approach

Antimycobacterial and Anti-Inflammatory Activities of Substituted Chalcones Focusing on an Anti-Tuberculosis Dual Treatment Approach

Tuberculosis (TB) remains a serious public health problem aggravated by the emergence of M. tuberculosis (Mtb) strains resistant to multiple drugs (MDR). Delay in TB treatment, common in the MDR-TB cases, can lead to deleterious life-threatening inflammation in susceptible hyper-reactive individuals...

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Bibliographic Details
Main Authors: Thatiana Lopes Biá Ventura, Sanderson Dias Calixto, Bárbara de Azevedo Abrahim-Vieira, Alessandra Mendonça Teles de Souza, Marcos Vinícius Palmeira Mello, Carlos Rangel Rodrigues, Leandro Soter de Mariz e Miranda, Rodrigo Octavio Mendonça Alves de Souza, Ivana Correa Ramos Leal, Elena B. Lasunskaia, Michelle Frazão Muzitano
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
tuberculosis
Mycobacterium
inflammation
chalcone
Online Access:http://www.mdpi.com/1420-3049/20/5/8072

Internet

http://www.mdpi.com/1420-3049/20/5/8072

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