Ranking of persister genes in the same Escherichia coli genetic background demonstrates varying importance of individual persister genes in tolerance to different antibiotics

Ranking of persister genes in the same Escherichia coli genetic background demonstrates varying importance of individual persister genes in tolerance to different antibiotics

Despite the identification of many genes and pathways involved in the persistence phenomenon of bacteria, the relative importance of these genes in a single organism remains unclear. Here, using Escherichia coli as a model, we generated mutants of 21 known candidate persister genes and compared the...

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Bibliographic Details
Main Authors: Nan eWu, Lei eHe, Peng eCui, Wenjie eWang, Youhua eYuan, Shuang eLiu, Tao eXu, Jing eWu, Wenhong eZhang, Ying eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
Persistence
antibiotics
knockout mutant
ranking
persister gene
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01003/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.01003/full

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