Dynamics of tumor hypoxia in response to patupilone and ionizing radiation.

Tumor hypoxia is one of the most important parameters that determines treatment sensitivity and is mainly due to insufficient tumor angiogenesis. However, the local oxygen concentration in a tumor can also be shifted in response to different treatment modalities such as cytotoxic agents or ionizing...

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Bibliographic Details
Main Authors: Katrin Orlowski, Carla Rohrer Bley, Martina Zimmermann, Van Vuong, Daniel Hug, Alex Soltermann, Angela Broggini-Tenzer, Martin Pruschy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519688?pdf=render