Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients

Detection of MET Alterations Using Cell Free DNA and Circulating Tumor Cells from Cancer Patients

MET alterations may provide a potential biomarker to evaluate patients who will benefit from treatment with MET inhibitors. Therefore, the purpose of the present study is to investigate the utility of a liquid biopsy-based strategy to assess MET alterations in cancer patients. We analyzed <i>M...

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Bibliographic Details
Main Authors: Patricia Mondelo-Macía, Carmela Rodríguez-López, Laura Valiña, Santiago Aguín, Luis León-Mateos, Jorge García-González, Alicia Abalo, Oscar Rapado-González, Mercedes Suárez-Cunqueiro, Angel Díaz-Lagares, Teresa Curiel, Silvia Calabuig-Fariñas, Aitor Azkárate, Antònia Obrador-Hevia, Ihab Abdulkader, Laura Muinelo-Romay, Roberto Diaz-Peña, Rafael López-López
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
met protein expression
<i>met</i> amplification
circulating free dna (cfdna)
circulating tumor cells (ctcs)
targeted therapy
<i>met</i> copy number
Online Access:https://www.mdpi.com/2073-4409/9/2/522

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https://www.mdpi.com/2073-4409/9/2/522

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