3D multi-cell simulation of tumor growth and angiogenesis.

We present a 3D multi-cell simulation of a generic simplification of vascular tumor growth which can be easily extended and adapted to describe more specific vascular tumor types and host tissues. Initially, tumor cells proliferate as they take up the oxygen which the pre-existing vasculature suppli...

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Bibliographic Details
Main Authors: Abbas Shirinifard, J Scott Gens, Benjamin L Zaitlen, Nikodem J Popławski, Maciej Swat, James A Glazier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2760204?pdf=render