Proteomic changes in rat spermatogenesis in response to in vivo androgen manipulation; impact on meiotic cells.

The production of mature sperm is reliant on androgen action within the testis, and it is well established that androgens act on receptors within the somatic Sertoli cells to stimulate male germ cell development. Mice lacking Sertoli cell androgen receptors (AR) show late meiotic germ cell arrest, s...

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Bibliographic Details
Main Authors: Peter G Stanton, Pavel Sluka, Caroline F H Foo, Andrew N Stephens, A Ian Smith, Robert I McLachlan, Liza O'Donnell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408499?pdf=render