Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

Antibodies that target the N-terminal domain (NTD) of the MERS-CoV spike remain poorly characterized. Here, Zhou et al. report the structural and functional analysis of the NTD-targeting mAb 7D10 and show that it synergizes with antibodies targeting the receptor-binding domain against different MERS...

Full description

Bibliographic Details
Main Authors: Haixia Zhou, Yingzhu Chen, Shuyuan Zhang, Peihua Niu, Kun Qin, Wenxu Jia, Baoying Huang, Senyan Zhang, Jun Lan, Linqi Zhang, Wenjie Tan, Xinquan Wang
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10897-4

Internet

https://doi.org/10.1038/s41467-019-10897-4

Similar Items