Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells and the Bone Marrow Microenvironment

Inflamm-Aging of Hematopoiesis, Hematopoietic Stem Cells and the Bone Marrow Microenvironment

All hematopoietic and immune cells are continuously generated by hematopoietic stem cells (HSCs) and progenitors (HPCs) through highly organized processes of stepwise lineage commitment. In the steady state, HSCs are mostly quiescent, while HPCs are actively proliferating and contributing to daily h...

Full description

Bibliographic Details
Main Authors: Larisa V. Kovtonyuk, Kristin Fritsch, Xiaomin Feng, Markus G. Manz, Hitoshi Takizawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Immunology
Subjects:
Inflammation
Ageing
cytokine
pathogen recognition receptor
niche
hematopoietic stem cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00502/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00502/full

Similar Items