Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor.

It is well established that acute activation of members of the protein kinase C (PKC) family induced by activation of cellular receptors can transduce extracellular stimuli to intracellular signaling. However, the functions of sustained activation of PKC are not well studied. We have previously show...

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Bibliographic Details
Main Authors: Mengling Liu, Jolanta Idkowiak-Baldys, Patrick L Roddy, Aleksander Baldys, John Raymond, Christopher J Clarke, Yusuf A Hannun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823608?pdf=render