Differential Inhibition of the Brain Acetylcholinesterase Molecular Forms Following Sarin, Soman and VX Intoxication in Laboratory Rats

The female Wistar rats were intoxicated (i.m.) with sarin, soman and VX in doses equal to 1xLD50 and pontomedullar areas of the brain were prepared, homogenized, centrifuged and in these samples, acetylcholinesterase (AChE, EC 3.1.1.7) activities were determined. In the same samples, AChE was separa...

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Bibliographic Details
Main Author: Jiří Bajgar
Format: Article
Language:English
Published: Karolinum Press 1997-01-01
Series:Acta Medica
Subjects:
Rat
Online Access:https://actamedica.lfhk.cuni.cz/40/4/0089/