A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell Cycle Arrest and Apoptosis in Small Cell Lung Cancer

A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell Cycle Arrest and Apoptosis in Small Cell Lung Cancer

11-Dehydrosinulariolide, an active compound that is isolated from the cultured soft coral <i>Sinularia flexibilis</i>, has been suggested to show anti-tumor biological characteristics according to previous studies. However, its potential effect on small cell lung cancer (SCLC) remains un...

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Bibliographic Details
Main Authors: Yu-Chao Lin, Jui-Hsin Su, Shih-Chao Lin, Chia-Che Chang, Te-Chun Hsia, Yu-Tang Tung, Chi-Chien Lin
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Marine Drugs
Subjects:
11-dehydrosinulariolide
soft coral
small cell lung cancer
apoptosis
cell cycle arrest
Online Access:https://www.mdpi.com/1660-3397/16/12/479

Internet

https://www.mdpi.com/1660-3397/16/12/479

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