Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats

ABSTRACT Objective: Hypothalamic inflammation and glial fibrillary acidic protein (GFAP) overexpression in astrocytes are well described in obese animals, as are some cognitive and memory deficits. As the hippocampus plays important roles in the consolidation of information, this investigation aime...

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Bibliographic Details
Main Authors: Eduardo Fernandes Bondan, Carolina Vieira Cardoso, Maria de Fátima Monteiro Martins, Rosemari Otton
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO)
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019000900601&lng=en&tlng=en