<i>Rheum rhaponticum</i> Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model

<i>Rheum rhaponticum</i> Root Extract Improves Vasomotor Menopausal Symptoms and Estrogen-Regulated Targets in Ovariectomized Rat Model

Ovarian insufficiency and ovariectomy are characterized by deregulated heat loss mechanisms. Unlike hormone therapy, ERr 731 (a standardized botanical extract of Siberian rhubarb <i>Rheum rhaponticum</i> L. high in rhaponticin) acts like a selective estrogen receptor modulator for ERβ re...

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Bibliographic Details
Main Authors: Mickey Wilson, Veera Konda, Kathryn Heidt, Thirumurugan Rathinasabapathy, Anuradha Desai, Slavko Komarnytsky
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
postmenopausal
estrogens
hot flashes
HRT
ERr 731
Online Access:https://www.mdpi.com/1422-0067/22/3/1032

Internet

https://www.mdpi.com/1422-0067/22/3/1032

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