A Method to Estimate the Efficacy vs. Effectiveness in Meta-Analysis of Clinical Trials with Different Adherence Scenarios: A Monte Carlo Simulation Study in Nutrition

Randomized clinical trials (RCTs) evaluating the effectiveness of interventions to promote fruit and vegetable (FV) consumption usually report intention-to-treat (ITT) analysis as the main outcome. These analyses compare the randomly assigned groups and accept that some individuals may not follow th...

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Bibliographic Details
Main Authors: Miguel Ángel López-Espinoza, José Antonio Lozano-Lozano, David Prieto-Merino
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Nutrients
Subjects:
SBP
DBP
Online Access:https://www.mdpi.com/2072-6643/13/7/2352