The chromatin remodelling complex B-WICH changes the chromatin structure and recruits histone acetyl-transferases to active rRNA genes.

The chromatin remodelling complex B-WICH, which comprises the William syndrome transcription factor (WSTF), SNF2h, and nuclear myosin 1 (NM1), is involved in regulating rDNA transcription, and SiRNA silencing of WSTF leads to a reduced level of 45S pre-rRNA. The mechanism behind the action of B-WICH...

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Bibliographic Details
Main Authors: Anna Vintermist, Stefanie Böhm, Fatemeh Sadeghifar, Emilie Louvet, Anethe Mansén, Pergiorgio Percipalle, Ann-Kristin Ostlund Farrants
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084792?pdf=render