On-Chip DNA Methylation Analysis Using Osmium Complexation

The development of a reaction for detecting the presence/absence of one methyl group in a long DNA strand is a chemically and biologically challenging research subject. A newly designed chemical assay on a chip for the typing of DNA methylation has been developed. A methylation-detection probe fixed...

Full description

Bibliographic Details
Main Authors: Kaori Sugizaki, Tadashi Umemoto, Akimitsu Okamoto
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2011/480570