Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat

Objective. Severe hepatic ischemia reperfusion injury (IRI) can result in poor short- and long-term graft outcome after transplantation. The way to improve the viability of livers from donors after circulatory death (DCD) is currently limited. The aim of the present study was to explore the protecti...

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Bibliographic Details
Main Authors: Zhongzhong Liu, Xingjian Zhang, Qi Xiao, Shaojun Ye, Chin-Hui Lai, Jun Luo, Xiaoying Huang, Wei Wang, Cheng Zeng, Zibiao Zhong, Xiaoli Fan, Zhiping Xia, Yan Xiong, Xinfang Mao, Qifa Ye, Yanfeng Wang
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/3861914

Internet

http://dx.doi.org/10.1155/2017/3861914

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