ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells

Abstract Background Oroscomucoid 3 (ORMDL3) has been linked to susceptibility of childhood asthma and respiratory viral infection. Polyinosinic-polycytidylic acid (poly I:C) is a synthetic analog of viral double-stranded RNA, a toll-like receptor 3 (TLR3) ligand and mimic of viral infection. Methods...

Full description

Bibliographic Details
Main Authors: Gemma Laura, Yi Liu, Kieran Fernandes, Saffron A. G. Willis-Owen, Kazuhiro Ito, William O. Cookson, Miriam F. Moffatt, Youming Zhang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Pulmonary Medicine
Subjects:
ORMDL3
Poly I:C
TLR3
Epithelial cell
Inflammatory response
Online Access:https://doi.org/10.1186/s12890-021-01496-5

Internet

https://doi.org/10.1186/s12890-021-01496-5

Similar Items