Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study

Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study

Abstract Background Immune checkpoint inhibitors (ICI) produce durable antitumor responses but provoke autoimmune toxicities, including uncommon but potentially devastating neurologic toxicities. The clinical features, including the spectrum, timing, and outcomes, of ICI-induced neurologic toxicitie...

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Bibliographic Details
Main Authors: Douglas B. Johnson, Ali Manouchehri, Alexandra M. Haugh, Henry T. Quach, Justin M. Balko, Benedicte Lebrun-Vignes, Andrew Mammen, Javid J. Moslehi, Joe-Elie Salem
Format: Article
Language:English
Published: BMJ Publishing Group 2019-05-01
Series:Journal for ImmunoTherapy of Cancer
Subjects:
Neurotoxicity
PD-1
CTLA-4
PD-L1
Neuropathy
Encephalitis
Online Access:http://link.springer.com/article/10.1186/s40425-019-0617-x

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http://link.springer.com/article/10.1186/s40425-019-0617-x

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