Tetrodotoxin as a Tool to Elucidate Sensory Transduction Mechanisms: The Case for the Arterial Chemoreceptors of the Carotid Body

Tetrodotoxin as a Tool to Elucidate Sensory Transduction Mechanisms: The Case for the Arterial Chemoreceptors of the Carotid Body

Carotid bodies (CBs) are secondary sensory receptors in which the sensing elements, chemoreceptor cells, are activated by decreases in arterial PO2 (hypoxic hypoxia). Upon activation, chemoreceptor cells (also known as Type I and glomus cells) increase their rate of release of neurotransmitters that...

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Bibliographic Details
Main Authors: Constancio Gonzalez, Ana Obeso, Ana Isabel Caceres, Asuncion Rocher
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Marine Drugs
Subjects:
carotid body
O2-sensing
tetrodotoxin
TTX
veratridine
dihydropyridine
catecholamine
Online Access:http://www.mdpi.com/1660-3397/9/12/2683/

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http://www.mdpi.com/1660-3397/9/12/2683/

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