Impact of crowded environments on binding between protein and single-stranded DNA

Abstract The concept of Molecular Crowding depicts the high density of diverse molecules present in the cellular interior. Here, we determine the impact of low molecular weight and larger molecules on binding capacity of single-stranded DNA (ssDNA) to the cold shock protein B (CspB). Whereas structu...

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Bibliographic Details
Main Authors: Birgit Köhn, Patricia Schwarz, Pernilla Wittung-Stafshede, Michael Kovermann
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97219-1