Mechanisms of palmitate-induced cell death in human osteoblasts

Summary Lipotoxicity is an overload of lipids in non-adipose tissues that affects function and induces cell death. Lipotoxicity has been demonstrated in bone cells in vitro using osteoblasts and adipocytes in coculture. In this condition, lipotoxicity was induced by high levels of saturated fatty ac...

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Bibliographic Details
Main Authors: Krishanthi Gunaratnam, Christopher Vidal, Ross Boadle, Chris Thekkedam, Gustavo Duque
Format: Article
Language:English
Published: The Company of Biologists 2013-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/12/1382