Mutation status of refractory to imatinib patients with chronic myeloid leukemia

Mutation status of refractory to imatinib patients with chronic myeloid leukemia

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<p>Mutation status of 36 chronic myeloid leukemia (CML) patients in chronic phase with primary and secondary imatinib resistance was analyzed. BCR-ABL mutations identified by direct DNA sequencing. BCR-ABL kinase domain mutations were detected in 30.5 % (11 of 36) of those patients. Most of id...

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Bibliographic Details
Main Authors: E. G. Ovsyannikova, K. D. Kaplanov, T. Yu. Klitochenko, A. V. Misyurin, I. L. Davydkin, L. V. Zaklyakova, E. A. Popov, B. N. Levitan
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Onkogematologiâ
Subjects:
chronic myeloid leukemia
BCR-ABL mutations
resistance
imatinib
Online Access:http://oncohematology.abvpress.ru/index.php/ongm/article/view/72

Internet

http://oncohematology.abvpress.ru/index.php/ongm/article/view/72

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