Strategies to stimulate mobilization and homing of endogenous stem and progenitor cells for bone tissue repair

The gold standard for the treatment of critical sized bone defects is autologous or allogenic bone graft. This has several limitations including donor site morbidity and the restricted supply of graft material. Cell-based tissue engineering strategies represent an alternative approach. Mesenchymal s...

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Bibliographic Details
Main Authors: Marietta eHerrmann, Sophie eVerrier, Mauro eAlini
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00079/full