CCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual.

BACKGROUND: Homozygosity (Delta32/Delta32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease progression. METHODOLOGY/PRINCIPAL FINDINGS: We genotyped a population o...

Full description

Bibliographic Details
Main Authors: Djin-Ye Oh, Heiko Jessen, Claudia Kücherer, Konrad Neumann, Nari Oh, Gabriele Poggensee, Barbara Bartmeyer, Arne Jessen, Axel Pruss, Ralf R Schumann, Osamah Hamouda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2453227?pdf=render