PPAR-Alpha Agonist Used at the Acute Phase of Experimental Ischemic Stroke Reduces Occurrence of Thrombolysis-Induced Hemorrhage in Rats

The impact of fenofibrate, a peroxisome proliferator-activated receptor-alpha (PPAR-α) agonist, on the risk of thrombolysis-induced hemorrhage during the acute phase of stroke in a rat model of stroke was studied. One-hour middle cerebral artery occlusion followed by thrombolysis with tissue plasmin...

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Bibliographic Details
Main Authors: Sophie Gautier, Thavarak Ouk, Maud Pétrault, Olivier Pétrault, Vincent Bérézowski, Régis Bordet
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2015/246329