Role of Klotho in Chronic Calcineurin Inhibitor Nephropathy

Calcineurin inhibitors (CNIs) are the most popular immunosuppressants in organ transplantation, but nephrotoxicity is a major concern. The common mechanism underlying chronic CNI nephropathy is oxidative stress, and the process of chronic CNI nephropathy is similar to that of aging. Current studies...

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Bibliographic Details
Main Authors: Kang Luo, Sun Woo Lim, Yi Quan, Sheng Cui, Yoo Jin Shin, Eun Jeong Ko, Byung Ha Chung, Chul Woo Yang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/1825018