Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse.

Pre-mRNA splicing, the removal of introns from RNA, takes place within the spliceosome, a macromolecular complex composed of five small nuclear RNAs and a large number of associated proteins. Spliceosome assembly is modulated by the 5' and 3' splice site consensus sequences situated at the...

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Bibliographic Details
Main Authors: Massimo Buvoli, Ada Buvoli, Leslie A Leinwand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1855434?pdf=render