Distinct DNA binding sites contribute to the TCF transcriptional switch in C. elegans and Drosophila.

Regulation of gene expression by signaling pathways often occurs through a transcriptional switch, where the transcription factor responsible for signal-dependent gene activation represses the same targets in the absence of signaling. T-cell factors (TCFs) are transcription factors in the Wnt/ß-cate...

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Bibliographic Details
Main Authors: Chandan Bhambhani, Aditi J Ravindranath, Remco A Mentink, Mikyung V Chang, Marco C Betist, Yaxuan X Yang, Sandhya P Koushika, Hendrik C Korswagen, Ken M Cadigan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3916239?pdf=render