Distinct DNA binding sites contribute to the TCF transcriptional switch in C. elegans and Drosophila.
Regulation of gene expression by signaling pathways often occurs through a transcriptional switch, where the transcription factor responsible for signal-dependent gene activation represses the same targets in the absence of signaling. T-cell factors (TCFs) are transcription factors in the Wnt/ß-cate...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3916239?pdf=render |