Biophysical description of multiple events contributing blood leukocyte arrest on endothelium

Blood leukocytes have a remarkable capacity to bind to and stop on specific blood vessel areas. Many studies have disclosed a key role of integrin structural changes following the interaction of rolling leukocytes with surface-bound chemoattractants. However, the functional significance of structura...

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Bibliographic Details
Main Authors: Philippe eRobert, Dominique eTouchard, Pierre eBongrand, Anne ePierres
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00108/full