Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes

Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes

Objective: MicroRNAs (miRNAs) are increasingly recognized as fine-tuning regulators of metabolism, and are dysregulated in several disease conditions. With their capacity to rapidly change gene expression, miRNAs are also important regulators of development and cell differentiation. In the current s...

Full description

Bibliographic Details
Main Authors: Tora I. Henriksen, Peter K. Davidsen, Maria Pedersen, Heidi S. Schultz, Ninna S. Hansen, Therese J. Larsen, Allan Vaag, Bente K. Pedersen, Søren Nielsen, Camilla Scheele
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Molecular Metabolism
Subjects:
Satellite cell
MicroRNA
Diabetes
Muscle
Human
Myogenesis
muscle stem cells
p53
miR-23b
miR-27b
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817302211

Internet

http://www.sciencedirect.com/science/article/pii/S2212877817302211

Similar Items