Epigenetic Mechanisms Involved in Cisplatin-Induced Nephrotoxicity: An Update

Epigenetic Mechanisms Involved in Cisplatin-Induced Nephrotoxicity: An Update

Cisplatin is an antineoplastic drug used for the treatment of many solid tumors. Among its various side effects, nephrotoxicity is the most detrimental. In recent years, epigenetic regulation has emerged as a modulatory mechanism of cisplatin-induced nephrotoxicity, involving non-coding RNAs, DNA me...

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Bibliographic Details
Main Authors: Pía Loren, Nicolás Saavedra, Kathleen Saavedra, Tomás Zambrano, Patricia Moriel, Luis A. Salazar
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
epigenetics
non-coding RNA
DNA methylation
histone modification
nephrotoxicity
Online Access:https://www.mdpi.com/1424-8247/14/6/491

Internet

https://www.mdpi.com/1424-8247/14/6/491

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