Exogenous supply of Hsp47 triggers fibrillar collagen deposition in skin cell cultures in vitro
Abstract Background Collagen is a structural protein that provides mechanical stability and defined architectures to skin. In collagen-based skin disorders this stability is lost, either due to mutations in collagens or in the chaperones involved in collagen assembly. This leads to chronic wounds, s...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | BMC Molecular and Cell Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12860-020-00267-0 |